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KEYNOTE SPEAKER

Gabrielle Lyon, DO

Presentation topic:

Forever Strong: The Clinical Case for Skeletal Muscle as the Organ of Longevity

Day 2 | 17 Oct | 8:45 AM – 10:00 AM

Keynote + Q&A

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About the topic:

Everything modern medicine has taught us about metabolic health, aging, and disease prevention is built on the wrong foundation. We've treated adiposity as the primary driver of chronic disease, when the clinical signal hiding in plain sight is skeletal muscle insufficiency. After years of treating complex patients across metabolic, autoimmune, and neurodegenerative presentations, Dr. Gabrielle Lyon identified the pattern that now defines her clinical model: these patients weren't overfat. They were undermuscled. That distinction changes everything about how practitioners assess, prescribe, and prognosticate.

Learning objectives:

In this keynote, Dr. Lyon translates the science of Muscle-Centric Medicine® into a clinical framework ready for Monday-morning implementation.

  • Reframe sarcopenia, anabolic resistance, and protein insufficiency as upstream drivers of the chronic conditions filling your schedule
  • Apply evidence-based protein thresholds and leucine targets for stimulating muscle protein synthesis across age groups
  • Prescribe resistance training with the same rigor as pharmacotherapy: how to write it, progress it, and integrate it with supplementation and nutritional interventions
  • Identify anabolic resistance early through targeted lab markers and functional assessments, before it manifests as frailty, metabolic dysfunction, or neurodegenerative disease
  • Shift the exam-room conversation from weight loss to muscle gain, a reframe that improves adherence, outcomes, and the therapeutic relationship

About the speaker:

Dr. Gabrielle Lyon is an accomplished, board-certified family physician and a distinguished New York Times bestselling author, lauded for her latest work, FOREVER STRONG: A New, Science-Based Strategy for Aging Well. Her book’s exceptional success has also earned her the esteemed titles of Wall Street Journal and USA Today bestselling author.

At the forefront of modern medicine, Dr. Lyon is leading a revolutionary movement focusing on the body’s largest organ—skeletal muscle. Her mission is to promote longevity and combat the pervasive threats of obesity, heart disease, and diabetes by optimizing muscle health.

Dr. Lyon’s rich background encompasses a dual research and clinical fellowship in geriatrics and nutritional sciences at Washington University, complemented by her undergraduate training in nutritional sciences at the University of Illinois. As an authority in the practical application of protein types and levels for health, performance, aging, and disease prevention, she is highly sought after as an educator.

Through her thriving private practice, influential YouTube channel, captivating podcast, and bestselling book, Dr. Lyon poses a fundamental question: How can we foster strength not only in the weight room but in our daily lives? With unwavering dedication to cultivating consistent dietary and lifestyle habits, she empowers individuals to prioritize self-care and better support their loved ones, contributing to a world of enhanced strength and well-being.

XYMOGEN XPERIENCE

Fitter. Smarter. Stronger. Longer.

October 16 - 18, 2026

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